Tuberculosis Clinical Prediction Rule

The goal of the model is to allow adequate respiratory precautions on hospital admission of contagious patients while minimizing the isolation of patients without Tuberculosis.

TB risk factors or chronic symptoms (history of exposure to an individual with TB, institutionalization in last 3 years, homelessness, significant weight loss, night sweats for minimum of 3 weeks, symptoms of malaise or weakness for more than 3 months, persistent fever, presence of cough, hemoptysis)
Positive PPD tuberculin test result
Shortness of breath
Crackles noted during examination
Upper lobe consolidation
Derivation Reference:

Wisnivesky, J.P., Kaplan, J., Henschke, C., McGinn, T.G., Crystal, R.G. Evaluation of Clinical Parameters to Predict Mycobacterium Tuberculosis in Inpatients. Archives of Internal Medicine 160, no. 16 (September 11, 2000): 2471–76.

Validation Reference:

Wisnivesky, J.P., Kaplan, J., Henschke, C., Balentine, J., Willner, C., Deloire, A. M., McGinn, T.G. Prospective Validation of a Prediction Model for Isolating Inpatients With Suspected Pulmonary Tuberculosis. Archives of Internal Medicine 165, no. 4 (February 28, 2005): 453–57. doi:10.1001/archinte.165.4.453.